Understanding the basics of CBDA and CBGA

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CBDA and CBDGA are the precursors to their respective cannabinoids, meaning they only exist in preprocessed plants of cannabis and hemp. Thus, CBDA and CBDGA are the living components of the plant, meaning you won’t find them in your typical hemp or cannabis wellness supplement. 

What is CBDA?

The body’s endocannabinoid system, including the nervous system and immune system, consists of cannabinoids, which function by interacting with those receptors. CBDA, also known as cannabidiol acid, is found in cannabis plants’ stems, leaves, and flowers. When the plant is activated (by heating), a component of it is removed, which activates CBD, CBDA has similar properties, but it is less versatile than CBD. Raw CBD is CBDA, which is hard to find, but it’s available. While CBDA has not undergone extensive research, individuals can extract the substance by juicing the plant material, and individuals can add it to food, drinks, tinctures, and concentrated herbal extracts.

CBDA’s potential medical benefits

In contrast to most cannabinoids, CBDA does not bind directly to the CB1 or CB2 receptors but inhibits the cyclooxygenase-2 (COX-2) enzyme. As a result, CBDA may reduce inflammation associated with injury or infection by inhibiting COX-2 enzymes.

What is CBGA?

For over 50 years, scientists have known about cannabigerol (CBG), and 30 years later, Japanese researchers discovered it was a precursor to CBGA. Despite the long history, minimal research has taken place on CBGA. CBDGA or cannabigerolic acid is considered the mother cannabinoid since it produces CBD, CBDA, and THC. A compound known as CBGA is similar to other cannabinoids. CBGA is converted to raw molecules, after which it’s transformed into THC through enzymes called synthases.

Potential Medical Benefits of CBGA

CBGA has yet to receive much medical research. Nevertheless, early studies suggest that it may prove useful in preventing cardiovascular disease, metabolic disorders, and colon cancer in the future.

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